Towards purely inorganic clusters in medicine: Biocompatible divalent cations as counterions of cobaltabis(dicarbollide) and its iodinated derivatives

Monovalent cations, Cs+, and alkylammonium ([NR4]+) salts have traditionally been used to precipitate the anions of boranes, carborane metallocarborane clusters. In contrast, in body living organisms general, divalent cations a special relevance. this work, we isolate for first time cobaltabis(dicarbollide) biocompatible biological importance that can application both biology materials science. The preparation Ca2+, Mg2+ Fe2+ anionic iodinated nido-[C2B9H12]− as well its di-, tetra- octa-iodinated derivatives are reported. Ca2+ hard Lewis acids thus forms aqua ions if water is present synthetic process. All solid studied work contained molecules coordinated detected by IR TGA/DSC. medium acid Fe3+ one. acetone they do not coordinate anion, but solvated acetone. basically inorganic small provide at once cation simultaneously providing an X-ray contrast agent and/or bone defect repairing regenerative medicine.